Hazardous drinking – Alcohol and genetics
The idea that alcoholism is in the family has been around for centuries. In recent years, systematic studies and scientific research has begun to document the fact that some families may have a genetic predisposition to disease. But it is also carried out with further research, questions remain. Alcoholism is run by family history, because a child inherits genes that create a predisposition, or has a child learn to be an alcoholic, observing theirParents and other environmental factors? Or is it a combination of both?
My family experience in the fight against the devastating history of alcoholism and chemical dependency that strongly suggest that heredity is a factor, but there's also the environment. Our family history of alcoholism is at least four generations. My paternal grandmother had seven brothers and sisters who all died, both the ravages of alcoholism and spent the memory of his life inRecreation.
Over the years, when the children of brothers and sisters of my grandmother fought his personal battle with alcoholism, destroying patches of the disease continues to spread from generation to generation, life even more. This type of family history leads me to believe that for some families there are in fact predisposed to alcohol abuse and addiction, and deserves to be further studied. In the same way that former President Jimmy Carter has agreed to let the families in their study, the researchersHistory of pancreatic cancer to identify potential genes to be more families with histories of alcoholism, consider doing the same.
In the case of my grandmother, even if they are not an alcoholic, she married a man who is absolutely forbidden any type of alcohol consumption. We attributed this to their environment, because if the opportunity was very clear, he enjoyed drinking grandmother offered alcohol. Over time, our family was surprised by the fact that if the grandmother was, instead of who is marrieddrank a lot, even if they have had problems with alcohol. When my brothers and sisters reached adulthood (there were six children in the family), more than half of us would have had to deal with problems of alcoholism and drug abuse. This in turn led me to focus on legacy.
Recent research on the genetics of alcoholism on the jumps is a kind of genetic markers that allow may indicate a predisposition to addiction to alcohol. D-2 dopamine receptors in the brain provide pleasure or"Buzz" when they are stimulated by alcohol. If the number of D-2 receptors is depleted, are dedicated to their inclusion increased, reaching pleasurable response. Researchers at Brookhaven National Laboratory investigated alcohol-free laboratory mice and found that by restoring D-2 receptors in rats with a gene that desire was reduced after alcohol. After the gene therapy was stopped, the rats return to their intake of alcohol.
In 2004, Subhash C. Pandey, a psychiatrist with the University of Illinois atChicago, has studied the CREB gene. This gene produces a protein – CRP – which refers to areas of brain functioning, development and learning. This gene is also in the field of alcohol tolerance, dependence and withdrawal. The CREB gene is located in the central amygdala, found that the portion of the brain associated with arousal, control of autonomic responses associated with anxiety, emotional responses and the secretion of the hormone. Even the study of rats, reduced amounts of CREB were associated withincreased anxiety and preference for alcohol. In rats with a defect in the rat CREB gene increases their consumption of alcohol is 50%. Pandey concluded that "the CREB gene or alcoholism" crucial ", the fear of relief that causes alcohol dependence.
Each year, approximately 100,000 deaths are with alcoholism and 14 million Americans have gathered a drinking problem. These numbers are startling, and while the environment can also be a factor, I am convinced, geneticsKeep the answers to the problems of alcoholism and chemical dependency.
Resources
National Institute on Alcohol Abuse and Alcoholism – The Government site provides extensive research and resources for alcoholism, trends and current data. Published Alcohol Alert, genetics of alcoholism in 1992.
http://www.niaaa.nih.gov/
American Medical Association (AMA) – The newspaper for America's physicians
Addictive cocktail: Alcoholism and genetics of VictoriaStagg Elliott, 5 February 2001.
www.ama-assn.org
Genetics and alcoholism by the Associated Content (The People's Media Company) to:
www.associatedcontent.com
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